TIGR® Matrix is the world’s first long-term resorbable, 100% synthetic, surgical mesh. Its unique technology consisting of dual-stage degradation and full resorption, paired with ease of use, is a significant step forward in surgical mesh technology. Since it uses polymers common in medical devices since the 1970’s, and is 100% synthetic, its components are more than well documented and clinically proven.
Since it uses polymers common in medical devices since the 1970’s, and is 100% synthetic, its components are more than well documented and clinically proven.
Today, TIGR® Matrix finds use in many applications, e.g. breast reconstruction and abdominal wall reinforcement. Please visit the evidence section to view currently available clinical evidence.
Before using TIGR® Matrix read the Instructions For Use which accompany the product for indications, contraindications, warnings and precautions. TIGR® Matrix Surgical Mesh received 510(k) clearance by the FDA in 2010 and carries the CE-mark since 2011.
TIGR® Matrix is currently available in 3 sizes:
TIGR Matrix Surgical Mesh is available in three sizes:
|NSTM1015E||10 x 15 cm||2.4 g|
|NSTM1520E||15 x 20 cm||4.9 g|
|NSTM2030E||20 x 30 cm||9.6 g|
TIGR Matrix Surgical Mesh is knitted from two different synthetic resorbable fibers, possessing different degradation characteristics. The fast-resorbing fiber, making up approximately 40% of the matrix by weight, is a copolymer of glycolide, lactide, and trimethylene carbonate.
The slow-resorbing fiber, making up approximately 60% of the matrix by weight, is a copolymer of lactide, and trimethylene carbonate. Both fibers degrade by bulk hydrolysis once implanted, resulting in a decreasing strength retention followed by mass loss of the fibers. In vitro testing showed that the fast-resorbing fiber (glycolide, lactide, and trimethylene carbonate) loses its mechanical strength after 2 weeks and in vivo studies in the abdominal wall of sheep showed that the fast-resorbing fiber is fully absorbed after 4 months.
The same in vitro testing showed that the slow-resorbing fiber (lactide, and trimethylene carbonate) maintains its mechanical strength for 6 months and in vivo studies in the abdominal wall of sheep indicated that the slow-resorbing fiber is absorbed after approximately 36 months.
While TIGR Matrix Surgical Mesh will degrade and be fully metabolized in the human body after implantation, patients will be followed up according to normal hospital practice, please contact your doctor for further information.
There are no warnings or precautions directed to patients in regards to interference with external influences, medical examination or environmental conditions.
From monomer to medical device
TIGR® Matrix is produced from monomer(raw material) to finished medical device at Novus Scientific’s manufacturing plant in Uppsala, Sweden.
The Novus team of polymer chemists and engineers has developed the polymerization process based on their many years of experience in working with resorbable materials.
The subsequent two production steps – turning the polymers into fibers and warp-knitting them into a mesh – are also carried out in our own facilities, several of them in a clean-room environment.
Our quality control and development facilities ensure that we continuously improve our knowledge of resorbable polymers and maintain the high quality standards required for finished medical device products.
The development and manufacturing is certified according to ISO13485 and fulfills QSR requirements for medical devices.